HubSpot Inbox Actions: Spam vs Block

What is the difference between marking a conversation as spam or blocking it?

Mark as Spam: Marking an email as spam only applies to the current thread. The message/conversation/email will be moved into the filtered view (left sidebar). 

Block Sender: Blocking an email address will move any emails from them to the Filtered view. The message/conversation/email will be moved into the filtered view (left sidebar). 

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When should I mark an email as spam? 

If there is no option at the bottom of the email to Unsubscribe from the mailing list, take the time to mark the email as spam. 

There are laws that reputable companies will follow. One such law is the CAN-SPAM legislation. This law, enforced by the Federal Trade Commission, states clearly that you must include a clearly obvious way for subscribers to opt out of your commercial messages.

Blocking a domain may seem attractive because it will prevent any emails from the address to come through; however, each time a person marks a sender as a spammer the email system gives 'negative points' to the offending domain; once a certain number of spam reports are received then the domain will be blacklisted and all messages sent from the offending domain will automatically be identified as spam.